Apres Tablet

Apres Tablet is manufactured by United Chemicals & Pharmaceuticals Ltd. Apres Tablet contains 100 mg Atenolol. It is Beta-adrenoceptor blocking drugs, Beta-blockers class drug.

The synthesis of atenolol resulted from attempts to produce a β-adrenoceptor antagonist that would competitively block β1 (cardiac) receptors but have no effect on β2-receptors. It is classified as a β1 selective (cardioselective) β-adrenergic receptor antagonist with no membranestability activity and no partial agonist activity. It is markedly the most hydrophilic of the currently available β- blockers and thus penetrates the lipid of cell membranes poorly

Uses

Apres is used for: Hypertension, Angina pectoris, Cardiac arrhythmia, Myocardial infarction

Brand Name: Apres
Generic: Atenolol
Weight: 100 mg
Type: Tablet
Therapeutic Class: Beta-adrenoceptor blocking drugs, Beta-blockers
Manufacturer: United Chemicals & Pharmaceuticals Ltd
Price: 0.00
Last Updated: November 20, 2020 at 6:15 pm

Dosage

Apres contains Atenolol 100 mg. Apres Dosage:

Hypertension: 50 mg once daily, the daily dose can be raised to 100 to 200 mg.

Angina pectoris: 50 to 100 mg daily.

Cardiac arrhythmia: Apres in low dose, 25-50 mg once daily, can be used in combination with digoxin to control the ventricular rate in atrial fibration or atrial flutter which is refractory to digoxin alone.

 

Side Effects

In general, atenolol is well tolerated although in a small number of patients (approximately 2-3%) therapy must be withdrawn because of troublesome symptomatic adverse effects. The commonest of these are cold extrimities, fatigue, vivid dreams, insomnia, diarrhoea, constipation, impotence and paraesthesia. Bronchospasm has been occurred with atenolol although this is very much less common than with the non-selective β-blockers.

Precaution

Patients already on a β-blocker must be evaluated carefully before Apres is administered. Apres may aggravate peripheral arterial circulatory disorders. Impaired Renal Function: Caution should be excised.

Apres

Interaction

Catecholamine-depleting drugs (e.g., Reserpine) and Calcium channel blockers may have an additive effect when given with Apres. Clonidine and aspirin may have some drug reactions.

Pregnancy Lactation use

Pregnancy Category D. Caution should be exercised when Apres is administered to a nursing woman.

Contraindication

Apres is contraindicated for: Second and third degree heart block, Untreated heart failure, Overt cardiac failure, Cardiogenic shock.

Special Warning

Safety and effectiveness in pediatric patients have not been established.

Acute Overdose

Overdosage with Apres has been reported with patients surviving acute doses as high as 5 gm. One death was reported in a man who may have taken as much as 10 gm acutely.

Interaction with other Medicine

 

Storage Condition