Apeclo Tablet

Apeclo Tablet is manufactured by Apex Pharmaceuticals Ltd. Apeclo Tablet contains 100 mg Aceclofenac. It is Aceclofenac is a non-steroidal agent with antiinflammatory and analgesic properties. Its mode of action is largely based on inhibition of prostaglandin synthesis. Aceclofenac is a potent inhibitor of the enzyme cyclooxygenase, which is involved in the production of prostaglandins. It also stimulates cartilage matrix (glycosaminoglycans) synthesis. class drug.

Drugs for Osteoarthritis, Drugs used for Rheumatoid Arthritis, Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Uses

Apeclo is used for the relief of pain and inflammation in both acute and chronic pain like osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, dental pain, post-traumatic pain, low back pain, gynaecological pain etc.

Brand Name: Apeclo
Generic: Aceclofenac
Weight: 100 mg
Type: Tablet
Therapeutic Class: Aceclofenac is a non-steroidal agent with antiinflammatory and analgesic properties. Its mode of action is largely based on inhibition of prostaglandin synthesis. Aceclofenac is a potent inhibitor of the enzyme cyclooxygenase, which is involved in the production of prostaglandins. It also stimulates cartilage matrix (glycosaminoglycans) synthesis.
Manufacturer: Apex Pharmaceuticals Ltd
Price: 3.54
Last Updated: November 21, 2020 at 6:15 pm

Dosage

Apeclo contains Aceclofenac 100 mg. Apeclo Dosage:

Adults: The maximum recommended dose is 200 mg daily, taken as two separate 100 mg doses, one tablet in the morning and one in the evening.

Children: There is no clinical data on the use of aceclofenac in children.

Elderly: The pharmacokinetics of aceclofenac are not altered in elderly patients, therefore it is not considered necessary to modify the dose and dose frequency.

Renal insufficiency: There is no evidence that the dosage of aceclofenac needs to be modified in patients with mild renal impairment.

Hepatic insufficiency: The dose of aceclofenac should be reduced in patients with hepatic impairment. An initial daily dose of 100 mg should be administered.

 

Apeclo SR tablet:

The recommended dose is 200 mg once daily.

 

Side Effects

Generally aceclofenac is well tolerated. The majority of side effects observed have been reversible and of a minor nature and include gastrointestinal disorders (dyspepsia, abdominal pain, nausea and diarrhoea) and occasional occurance of dizziness. Dermatological side effects including pruritus and rash. Abnormal hepatic enzyme levels and raised serum creatinine have occasionally been reported.

Precaution

Apeclo should be administered with caution to patients with symptoms indicative of gastrointestinal disorders, with a history of peptic ulceration, ulcerative colitis, Crohn\'s disease, hepatic porphyria, and coagulation disorders. Patients suffering from severe hepatic impairment must be monitored.

Apeclo

Interaction

Lithium and Digoxin: Apeclo, like many NSAIDs may increase plasma concentrations of lithium and Digoxin.

Diuretics: Apeclo, like other NSAIDs, may interact the activity of diuretics.

Anticoagulants: Like other NSAIDs, Apeclo may enhance the activity of anticoagulant. Close monitoring of patients on combined anticoagulants and Apeclo therapy should be undertaken.

Methotrexate: Caution should be exercised if NSAIDs and Methotrexate are administered within 24 hours of each other, since NSAIDs may increase Methotrexate plasma levels, resulting in increased toxicity.

Pregnancy Lactation use

Pregnancy: There is no information on the use of aceclofenac during pregnancy. Apeclo should not be administered during pregnancy, unless there are compelling reasons for doing so. The lowest effective dose should be administered.

Lactation: There is no information on the secretion of aceclofenac in breast milk. The use of aceclofenac should therefore be avoided during lactation unless the potential benefits to the mother outweigh the possible risks to the children.

Contraindication

Apeclo should not be administered to patients with active or suspected peptic ulcer or gastro-intestinal bleeding. It should not be given to patients with moderate to severe renal impairment. Close medical surveillance is also imperative in patients suffering from severe impairment of hepatic function. It should not be prescribed during pregnancy, unless there are compelling reasons for doing so. The lowest effective dosage should be used. Apeclo should not be administered to patients previously sensitive to Apeclo or in whom aspirin or NSAIDs precipitate attacks of asthma, acute rhinitis or urticaria or who are hypersensitive to these drugs.

Special Warning

 

Acute Overdose

There is no human data available on the consequences of aceclofenac overdosage. After overdosage, following therapeutic measures to be taken: absorption should be prevented as soon as possible by means of gastric lavage and treatment with activated charcoal. Supportive and symptomatic treatment should be given for complications.

Interaction with other Medicine

 

Storage Condition

Keep at a cool and dry place, protected from light and moisture.

FAQ

What is Apeclo used for?

Apeclo is used for the relief of pain and inflammation in both acute and chronic pain like osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, dental pain, post-traumatic pain, low back pain, gynaecological pain etc.

Is Apeclo is a painkiller?

Anti-inflammatory painkillers like Apeclo are also called non-steroidal anti-inflammatory drugs (NSAIDs), or sometimes just 'anti-inflammatories'. Apeclo is prescribed for people with painful rheumatic conditions such as osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.

How safe is Apeclo?

Apeclo 100 mg orally twice daily, is a safe, effective, and convenient treatment for active AS.

Is Apeclo safe for kidneys?

Patients with mild to moderate renal impairment should be kept under surveillance, since the use of NSAIDs may result in deterioration of renal function. The lowest effective dose should be used and renal function monitored regularly. Effects on renal function are usually reversible on withdrawal of Apeclo.

Who should not take Apeclo?

Apeclo is not recommended if you have asthma or a history of asthma in your family. Impaired function of the kidney- Apeclo is not recommended if you have impaired kidney function. Impaired function of the liver- Use with caution with an initial dose of 100 mg once daily for mild liver failure.

Can Apeclo used for teeth pain?

Apeclo has anti-inflammatory properties similar to those of diclofenac and yields good results in the control of dental pain.

Does Apeclo make me sleepy?

It may cause dizziness, drowsiness or visual disturbances. Use caution while driving or doing anything that requires concentration. Avoid consuming alcohol while taking Apeclo as it can cause excessive drowsiness and increase your risk of stomach problems.

Does Apeclo increase blood pressure?

Apeclo may oppose the blood pressure lowering effects of certain medicines to treat high blood pressure, including the following: ACE inhibitors such as captopril.

Is Apeclo a muscle relaxant?

Apeclo is a non-steroidal anti-inflammatory drug (NSAID) which works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling). Thiocolchicoside is a muscle relaxant.

What is the Dosage of Apeclo?

Apeclo Dosage

Adults: The maximum recommended dose is 200 mg daily, taken as two separate 100 mg doses, one tablet in the morning and one in the evening.

Children: There is no clinical data on the use of Apeclo in children.

Elderly: The pharmacokinetics of Apeclo are not altered in elderly patients, therefore it is not considered necessary to modify the dose and dose frequency.

Renal insufficiency: There is no evidence that the dosage of Apeclo needs to be modified in patients with mild renal impairment.

Hepatic insufficiency: The dose of Apeclo should be reduced in patients with hepatic impairment. An initial daily dose of 100 mg should be administered.



Apeclo SR tablet:

The recommended dose is 200 mg once daily.

What is the Side Effects of Apeclo?

Generally Apeclo is well tolerated. The majority of side effects observed have been reversible and of a minor nature and include gastrointestinal disorders (dyspepsia, abdominal pain, nausea and diarrhoea) and occasional occurance of dizziness. Dermatological side effects including pruritus and rash. Abnormal hepatic enzyme levels and raised serum creatinine have occasionally been reported.

Is Apeclo safe during pregnancy?

There is no information on the use of Apeclo during pregnancy. Apeclo should not be administered during pregnancy, unless there are compelling reasons for doing so. The lowest effective dose should be administered.

Is Apeclo safe during breastfeeding?

There is no information on the secretion of Apeclo in breast milk. The use of Apeclo should therefore be avoided during lactation unless the potential benefits to the mother outweigh the possible risks to the children.