Anca Powder for Suspension
Anca Powder for Suspension is manufactured by Square Pharmaceuticals Ltd. Anca Powder for Suspension contains 250 mg/5 ml Cefprozil. It is Second generation Cephalosporins class drug.
Anca is a semi synthetic, second generation cephalosporin antibiotic. Anca is active in vitro against both gram positive and gram negative bacteria. The bactericidal activity of cefprozil results from the inhibition of cell wall synthesis via affinity for penicillin-binding proteins (PBPs).
Anca inhibits bacterial cell wall synthesis by binding to 1 or more of the penicillin binding proteins (PBPs) which in turn inhibit the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls, thus inhibiting cell wall biosynthesis and arresting cell wall assembly resulting in bacterial cell death.
Anca is used for the treatment of patients with mild to moderate infections caused by susceptible strains. Infections include:
- Lower respiratory tract infections: acute bronchitis, acute exacerbations of chronic bronchitis, community acquired pneumonia.
- Upper respiratory tract and ear infections: otitis media, sinusitis, tonsillitis and pharyngitis.
- Uncomplicated skin and soft tissue infections.
|Weight:||250 mg/5 ml|
|Type:||Powder for Suspension|
|Therapeutic Class:||Second generation Cephalosporins|
|Manufacturer:||Square Pharmaceuticals Ltd|
|Last Updated:||November 20, 2020 at 6:15 pm|
Table Of contents
Anca contains Cefprozil 250 mg/5 ml. Anca Dosage:
Adult: 500 mg daily as a single or in 2 divided doses, increased to 500 mg bid if necessary. Duration: 10 days.Child (6 month to 2 year):
- For otitis media: 15 mg/kg 12 hrly.
- For acute sinusitis: 7.5 mg/kg or 15 mg/kg 12 hrly.
- For pharyngitis or tonsillitis: 7.5 mg/kg 12 hourly.
Child (>2 yr):
- For skin and skin structure infections: 20 mg/kg daily. Max: 1 g daily.
Anca was usually well tolerated in controlled clinical trials. The most common adverse effects of cefprozil are diarrhea, nausea, vomiting, abdominal pain, rash, urticaria, dizziness, hyperactivity, insomnia, confusion etc.
History of hypersensitivity to penicillins and GI disease esp colitis. Renal impairment. Pregnancy and lactation.
May enhance the nephrotoxic effect of aminoglycosides. May enhance the anticoagulant effect of vit K antagonists. May diminish the therapeutic effect of BCG, typhoid vaccine and Na picosulfate. May increase serum concentrations w/ probenecid.
Pregnancy Lactation use
Pregnancy category B. There are no adequate and well-controlled studies in pregnant women. This drug should be used during pregnancy only if clearly needed. Small amounts of cefprozil (<0.3% of dose) have been detected in human milk following administration of a single 1 gram dose to lactating women. Caution should be exercised when cefprozil is administered to a nursing woman, since the effect of cefprozil on nursing infants is unknown.
Hypersensitivity to cephalosporin antibiotics.
Interaction with other Medicine
Store between 20-25°C. Reconstituted powder for suspension: Store between 2-8°C.