Anasec Capsule

Anasec Capsule is manufactured by Novo Healthcare and Pharma Ltd. Anasec Capsule contains 20 mg Omeprazole. It is Proton Pump Inhibitor class drug.

Anasec belongs to a class of antisecretory compounds, the substituted benzimidazoles, that suppress gastric acid secretion by specific inhibition of the H+/K+ ATPase enzyme system at the secretory surface of the gastric parietal cell. Because this enzyme system is regarded as the acid (proton) pump within the gastric mucosa, omeprazole has been characterized as a gastric acid-pump inhibitor, in that it blocks the final step of acid production. This effect is dose-related and leads to inhibition of both basal and stimulated acid secretion irrespective of the stimulus.


Anasec offers significant therapeutic gains in the treatment of acid related diseases. Healing rates are high in duodenal ulcer, gastric ulcer and erosive reflux oesophagitis; acid production is controlled effectively in Zollinger-Ellison Syndrome and symptom relief is prompt and sustained in all indications. Less clear-cut indications where benefit might be expected but where data are limited include:

  • Prevention of stress ulceration
  • Prevention of the acid aspiration syndrome
  • Treatment of upper gastro-intestinal bleeding

NOTE: In comparative studies, Anasec has been found to produce faster symptom relief and higher healing rates in a greater percentage of patients than either Cimetidine or Ranitidine, confirming the ‘therapeutic gains’ achievable with Anasec over existing therapies.

Brand Name: Anasec
Generic: Omeprazole
Weight: 20 mg
Type: Capsule
Therapeutic Class: Proton Pump Inhibitor
Manufacturer: Novo Healthcare and Pharma Ltd
Price: 7.00
Last Updated: June 9, 2021 at 3:31 pm


Anasec contains Omeprazole 20 mg. Anasec Dosage:


Duodenal Ulcer: 20 mg once daily for 4 weeks. In severe cases, 40 mg once daily for 4 weeks.

Gastric Ulcer: 20 mg once daily for 8 weeks. In severe cases, 40 mg once daily for 8 weeks.

Erosive Reflux Oesophagitis: 20 mg once daily for 4 weeks. For those not fully healed, to be continued for 4 more weeks. Refractory Reflux Oesophagitis: 40 mg once daily for 8 weeks. Zollinger-Ellison Syndrome: 60 mg once daily, adjusted individually and continued as long as necessary.Most patients will be effectively controlled with 20-120 mg daily. Dosage above 80 mg should be divided and given twice daily. Long-term maintenance treatment with Anasec is not recommended.

Impaired Renal or Hepatic Function: Adjustment is not required. Patients with severe liver disease should not require more than 20 mg Anasec daily

IV Injection-

Prophylaxis of acid aspiration: Anasec 40 mg to be given slowly (over a period of 5 minutes) as an intravenous injection, one hour before surgery.

Duodenal ulcer, gastric ulcer or reflux oesophagitis: In patients with duodenal ulcer, gastric ulcer or reflux oesophagitis where oral medication is inappropriate, Anasec IV 40 mg once daily is recommended.

Zollinger- Ellison syndrome (ZES): In patients with Zollinger-Ellison Syndrome the recommended initial dose of Anasec given intravenously is 60 mg daily. Higher daily doses may be required and the dose should be adjusted individually. When doses exceed 60 mg daily, the dose should be divided & given twice daily.

Powder for suspension: Should be taken on an empty stomach. Take at least 1 hr before a meal.

Capsule or Tablet: Should be taken with food. Take immediately before a meal. Patients should be cautioned that the capsules should not be opened, chewed or crushed and should be swallowed whole.

Delayed release Capsule or Tablet: Should be taken on an empty stomach. Take at least 1 hr before meals. Swallow whole, do not chewithcrush. For patients with difficulty swallowing, cap may be carefully opened & entire contents sprinkled in a spoonful of applesauce. Swallow drug/food mixt witho chewing immediately after prep. Drug/food mixt should not be stored for future use.

IV Injection: Anasec lyophilized powder and water for injection is for intravenous administration only and must not be given by any other route. Anasec IV injection should be given as a slow intravenous injection. The solution for IV injection is obtained by adding 10 ml water for injection to the vial containing powder. After reconstitution the injection should be given slowly over a period of at least 2 to 5 minutes at a maximum rate of 4 ml/minute. Use only freshly prepared solution. The solution should be used within 4 hours of reconstitution.

IV Infusion: Anasec IV infusion should be given as an intravenous infusion over a period of 20-30 minutes or more. The contents of one vial must be dissolved in 100 ml saline for infusion or 100 ml 5% Dextrose for infusion. The solution should be used within 12 hours when Anasec is dissolved in saline and within 6 hours when dissolved in 5% Dextrose. The reconstituted solution should not be mixed or co-administered in the same infusion set with any other drug.

Side Effects

Side effects reported with Anasec in clinical studies have included nausea, diarrhoea, constipation, flatulence, abdominal colic, paresthesia, dizziness and headache but are rare. Skin rashes, leukopenia and transient elevation of plasma activation of hepatic amino-transferases have been observed occasionally in few patients and there has been no consistent relationship with treatment.


Precautions: Symptomatic response to therapy with Anasec does not preclude the presence of gastric malignancy.

Warning: In long-term (2 years) studies in rats, Anasec produced a dose related increase in gastric carcinoid tumours. While available endoscopic evaluations and histologic examinations of biopsy specimens from human stomachs have not detected a risk from short-term exposure to Anasec, further human data on the effects of sustained hypochlorhydria and hypergastrinemia are needed to rule out the possibility of an increased risk for the development of tumours in humans receiving long-term therapy with Anasec.



Anasec can delay the elimination of Diazepam, Phenytoin and Warfarin. Monitoring of patients receiving Warfarin or Phenytoin is recommended and a reduction of Warfarin or Phenytoin dose may be necessary when Anasec is added to treatment. Anasec does not interfere with Theophylline or Propranolol metabolism.

Pregnancy Lactation use

Pregnancy: There are no adequate and well-controlled studies on the use of Anasec in pregnant women. Therapeutic doses during pregnancy are unlikely to pose a substantial teratogenic risk. Anasec should be used during pregnancy only if the potential benefit to pregnant women justifies the potential risk to the fetus.

Lactation: Anasec is excreted in human milk. Thus, a decision should be taken to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.


Anasec is contraindicated in patients with known hypersensitivity to any component of the formulation.

Special Warning

Renal Impairment: No dosage adjustment needed

Hepatic Impairment: 10-20 mg/day

Pediatric Use: Safety and effectiveness in children have not been established

Acute Overdose

Symptoms were transient, and no serious clinical outcome has been reported with Anasec overdose. No specific antidote for Anasec overdose is known. Anasec is extensively bound with protein and is, therefore, not readily dialyzable. In the event of overdose, treatment should be symptomatic and supportive.

Interaction with other Medicine


Storage Condition

Store in a cool and dry place. Keep out of the reach of children.


What is Anasec used for?

Anasec is used to treat conditions in which the stomach produces too much acid such as Zollinger-Ellison syndrome in adults. Prescription Anasec is used to allow the esophagus to heal and prevent further damage to the esophagus in adults and children 1 year of age and older with GERD.

What are the side effects of taking Anasec?

Anasec side effects are Rare:

  • Back, leg, or stomach pain
  • bleeding or crusting sores on the lips
  • blisters
  • bloody or cloudy urine
  • chills
  • continuing ulcers or sores in the mouth
  • difficult, burning, or painful urination
  • fever
  • frequent urge to urinate
  • general feeling of discomfort or illness
  • itching, skin rash
  • joint pain
  • loss of appetite
  • muscle aches or cramps
  • pain
  • red or irritated eyes
  • redness, tenderness, itching, burning, or peeling of the skin
  • sore throat
  • sores, ulcers, or white spots on the lips, in the mouth, or on the genitals
  • unusual bleeding or bruising
  • unusual tiredness or weakness

How long should I take Anasec?

Anasec is a delayed-release 20mg tablet, taken once a day (every 24 hours) for 14 days before eating. You should not take it for more than 14 days or repeat a 14-day course more often than every 4 months unless directed by a doctor. Do not crush, break, or chew the tablet.

Is it bad to take Anasec every day?

Sometimes you might need to take it for longer, even for many years. Some people do not need to take Anasec every day and take it only when they have symptoms. Once you feel better (often after a few days or weeks), you can stop taking it. But taking Anasec in this way is not suitable for everyone.

What foods neutralize stomach acid?

Foods that may help reduce your symptoms

  • Vegetables. Vegetables are naturally low in fat and sugar, and they help reduce stomach acid.
  • Ginger.
  • Oatmeal.
  • Noncitrus fruits.
  • Lean meats and seafood.
  • Egg whites.
  • Healthy fats.

How long before a meal should you take Anasec?

Take Anasec powder for oral suspension on an empty stomach at least 1 hour before a meal.

What can I take instead of Anasec?

These include proton pump inhibitors such as esomeprazole, omeprazole, pantoprazole and lansoprazole. The others are antacids such as Maalox, Mylanta and Tums; and H2 (histamine) receptor antagonists such as famotidine, and cimetidine.

Can Anasec make me gassy?

Common side effects may include: stomach pain, gas; nausea, vomiting, diarrhea; or. headache.

Why should not lie down after taking Anasec?

Do not lie down immediately after taking medicine, to make sure the pills have gone through the esophagus into the stomach. Notify your healthcare provider if you experience painful swallowing or feel that the medicine is sticking in your throat.

Why is Anasec taken before meals?

When therapy with Anasec or lansop- razole is indicated, medication should be taken before a meal for optimal control of daytime gastric acidity. the parietal cell is maximally stimulated as it is after a meal.

How do I cure GERD permanently?

Try to:

  • Maintain a healthy weight.
  • Stop smoking.
  • Elevate the head of your bed.
  • Don't lie down after a meal.
  • Eat food slowly and chew thoroughly.
  • Avoid foods and drinks that trigger reflux. ..
  • Avoid tight-fitting clothing.

Is it safe to take Anasec long term?

If you take Anasec for more than 3 months, the levels of magnesium in your blood may fall.

Low magnesium can make you feel tired, confused, dizzy and cause muscle twitches, shakiness and an irregular heartbeat. If you get any of these symptoms, tell your doctor.

Taking Anasec for more than a year may increase your chances of certain side effects, including:

  • bone fractures
  • gut infections
  • vitamin B12 deficiency – symptoms include feeling very tired, a sore and red tongue, mouth ulcers and pins and needles

If you take Anasec for longer than 1 year, your doctor will regularly check your health to see if you should carry on taking it.

Should I stop taking Anasec if I have diarrhea?

Stop using Anasec and call your doctor at once if you have: severe stomach pain, diarrhea that is watery or bloody; new or unusual pain in your wrist, thigh, hip, or back; seizure (convulsions);

How long does it take for stomach acid to return to normal?

For most people acid levels return to normal within one to two weeks.

Are there any side effects when I stop taking Anasec?

When Anasec is stopped, a common side effect is rebound acid secretion, where the acid secretion in your stomach increases significantly. This should return to normal within 2 weeks.

Is Anasec safe in pregnancy?

Usually, Anasec is safe to take during pregnancy.

Is Anasec safe during breastfeeding?

Usually, omeprazole is safe to take during breastfeeding.

How does Anasec work?

Anasec (Omeprazole) is a type of medicine called a proton pump inhibitor (PPI). Proton pumps are tiny substances in the lining of the stomach that help it make acid to digest food. Omeprazole prevents proton pumps working properly. This reduces the amount of acid the stomach makes.

When will I feel better after taking Anasec?

You should start to feel better within 2 to 3 days. It may take up to 4 weeks for Anasec to work properly, so you may still have some acid symptoms during this time. If you're self-treating, tell your doctor if you feel no better after taking Anasec for 2 weeks. They may want to do tests or change you to a different medicine.

Can I take painkillers with Anasec?

Yes, it's safe to take painkillers such as paracetamol or ibuprofen at the same time as Anasec. It's best to take ibuprofen with, or just after, a meal so it does not upset your stomach.

Are there other medicines like Anasec?

There are 4 other medicines that are similar to Anasec. They are:

  • lansoprazole
  • esomeprazole
  • pantoprazole
  • rabeprazole

Can I take Anasec with an antacid?

You can take Anasec with an antacid (for example, Gaviscon) if you need to, but leave a gap of 2 hours between them.

Will Anasec affect my fertility?

There's no clear evidence to suggest that taking Anasec will reduce fertility in either men or women. But speak to a pharmacist or your doctor if you're trying to get pregnant. They may want to review your treatment.

Will Anasec affect my contraception?

Anasec does not affect any type of regular contraception, including the combined pill. But if Anasec makes you sick (vomit), your contraceptive pills may not protect you from pregnancy. If this happens, follow the instructions in the leaflet that comes with your contraceptive pills.