Anaflex contains Naproxen Sodium. Anaflex uses:

Naproxen is indicated for the relief of symptoms of rheumatoid arthritis, both of acute flares and long term management of the disease. It is also used in the diseases of rheumatoid osteoarthritis (degenerative arthritis), ankylosing spondylitis, juvenile rheumatoid arthritis, tendinitis, brusitis, acute gout, acute musculoskeletal disorders (such as sprains, direct trauma and fibrositis), migraine and dysmenorrhoea.

Brand Name: Anaflex
Generic: Naproxen Sodium
Weight: 250 mg
Type: Suppository
Therapeutic Class: Drugs for Osteoarthritis, Drugs used for Rheumatoid Arthritis, Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Manufacturer: ACI Limited
Price: 0.00
Last Updated: May 2, 2021 at 3:45 pm

Introduction

Naproxen, a propionic acid derivative, is a prototypical NSAID. It reversibly inhibits the cyclooxygenase-1 and -2 (COX-1 and -2) enzymes, thus resulting in reduced synthesis of prostaglandin precursors. It can inhibit platelet aggregation, has anti-inflammatory, analgesic and antipyretic actions.

Anaflex

Dosage

Anaflex contains Naproxen Sodium 250 mg. Anaflex Dosage:

Tablet & Suppository (Adult)-

  • Rheumatic disorders: The usual initial dose of naproxen is 250 mg twice daily adjusted to 500 mg to 1000 mg daily in 2 divided doses.
  • Juvenile arthritis: A dose of 10 mg/kg body weight daily in 2 divided doses is used for children over 5 years of age.
  • Acute gout: An initial dose of 750 mg followed by 250 mg every 8 hours.
  • Dysmenorrhoea: 500 mg may be given initially followed by 250 mg in every 6-8 hours.

Syrup (Children over 5 years)-

  • In juvenile arthritis: The usual dosage of Naproxen is 10 mg/kg/day taken in two doses at 12-hour intervals is recommended.

Gel: Naproxen gel is to be applied 2-6 times a day as required and is not recommended for use in children.

 

Side Effects

Gastro-intestinal discomfort: nausea, diarrhoea and occasionally bleeding and ulceration.

Hypersensitivity reactions: notably with bronchospasm, rashes and angioedema.

CNS side effect: drowsiness, headache, fluid retention, vertigo, hearing disturbances such as tinnitus, photosensitivity.

A few instances of jaundice, impairment of renal function, thrombocytopenia, and agranulocytosis have been reported.

Precaution

Naproxen should be used with caution in patients with cardiac, hepatic and renal impairment, coagulation defect, and previous history of gastro-intestinal ulceration. The drug is contraindicated in patients with a history of hypersensitivity to aspirin or any other NSAID - which includes those in whom attacks of asthma, angioedema, urticaria or rhinitis have been precipitated by aspirin or any other NSAID.

Interaction

Antacid: The absorption of naproxen can be altered by antacids.

Aspirin: Plasma concentration of Naproxen can be reduced when aspirin is given concomitantly, this appeared to be due to increased exeretion of naproxen.

Diuretics: Naproxen diminish the effect of frusemide.

Probenecid: It increase the plasma concentration of Naproxen.

Pregnancy Lactation use

There are no well controlled studies in pregnant women. The drug should not be used during pregnancy unless clearly needed. Because of the possible adverse effects of prostaglandin inhibiting drugs on neonates, use in nursing mothers must be avoided.

Contraindication

Naproxen suppository in contraindicated in children under 12 years of age. The suppository is contraindicated also in patients with any inflammatory lesions of rectum or anus and in patients with recent history of rectal or anal bleeding.

Special Warning

 

Acute Overdose

Significant overdosage of the drug may be characterized by drowsiness, heartburn, indigestion, and nausea or vomiting. It is not known what dose of the drug would be life threatening.

Interaction with other Medicine

 

Storage Condition

Tablet: Protect from light and store below 30° C temperature in a dry place.

Suppository: Store below 25°C temperature.

Gel: Store in a cool and dry place protected from light.

Anaflex Suppository price in Bangladesh 0.00

FAQ

How quickly does Anaflex work?

You should start to feel better 1 hour after taking Anaflex. But it might take up to 3 days for Anaflex to work properly if you take it regularly twice a day.

Can Anaflex help depression?

Monotherapy with Anaflex and ibuprofen showed antidepressant effects after 6 weeks among 890 patients with active osteoarthritis. On the other hand; 12 month treatment with naproxen among 1,757 healthy users had no impact on depressive symptoms.

What organs does Anaflex affect?

Prostaglandins maintain the pressure in your kidneys so that these organs can filter the fluids in your body. A decrease in your level of prostaglandins from taking Aleve can cause problems with your kidney function. You may notice fluid retention or changes in how much you urinate.

Does Anaflex raise blood pressure?

NSAIDs can also raise your risk for heart attack or stroke, especially in higher doses. Common NSAIDs that can raise blood pressure include: Ibuprofen (Advil, Motrin) Naproxen (Aleve, Naprosyn)

What happens if I drink alcohol on Anaflex?

Do not drink alcohol while taking Anaflex. Alcohol can increase your risk of stomach bleeding caused by Anaflex. Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds.

What reduces the side effects of Anaflex?

Take oral Anaflex with or after food or with milk to help minimize the stomach side effects. Avoid alcohol to minimize the risk of stomach irritation. Have a lot of water and fluids when taking Anaflex. Avoid high-caloric foods.

Does Anaflex reduce swelling?

Anaflex is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve symptoms of arthritis (osteoarthritis, rheumatoid arthritis, or juvenile arthritis) such as inflammation, swelling, stiffness, and joint pain.

Can Anaflex cause hair loss?

Some anti-inflammatory drugs that can cause hair loss include Anaflex.

Can Anaflex reduce anxiety?

Patients receiving diclofenac, Anaflex, and ketoprofen had decreased anxiety and depression adverse drug reactions. Anxiety reports increased with meloxicam (Mobic), aspirin, and ibuprofen; celecoxib increased both depression and suicidal behavior.

Why should not lie down after taking Anaflex?

Do not lie down for at least 10 minutes after taking Anaflex. The dosage is based on your medical condition and response to treatment. To reduce your risk of stomach bleeding and other side effects, take this medication at the lowest effective dose for the shortest possible time.

Who should not take Anaflex?

Patients age 60 and older and patients with existing GI risks who take Anaflex or any other NSAID are at increased risk for stomach ulcers, GI bleeding, and other serious GI problems.

How many hours after taking Anaflex Can I drink alcohol?

Anaflex has a half-life of 12 to 17 hours. This means that the body will eliminate at least half of this chemical compound after this time has passed. At that point, an individual can begin to drink alcohol moderately.

Can I just stop taking Anaflex?

Prescription Anaflex oral tablet is a short-term drug treatment. It comes with risks if you don't take it as prescribed. If you stop taking the drug suddenly or don't take it at all: You may experience more pain and inflammation caused by your condition.

What happens if I take Anaflex and ibuprofen together?

Using ibuprofen together with Anaflex is generally not recommended. Combining these medications may increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

Can I drink coffee while taking Anaflex?

Avoid coffee, tea, cola, energy drinks or other sources of caffeine while taking Anaflex. They can add to the side effects of the caffeine in the medication.

What drugs should not be taken with Anaflex?

Serious Interactions of Anaflex include:

  • benazepril
  • captopril
  • enalapril
  • fosinopril
  • ketorolac
  • ketorolac intranasal
  • lisinopril
  • methotrexate
  • moexipril
  • pemetrexed
  • perindopril
  • quinapril
  • ramipril
  • tacrolimus
  • trandolapril

Is Anaflex an anti inflammatory?

Anaflex is used to relieve pain from various conditions such as headache, muscle aches, tendonitis, dental pain, and menstrual cramps. It also reduces pain, swelling, and joint stiffness caused by arthritis, bursitis, and gout attacks. This medication is known as a nonsteroidal anti-inflammatory drug (NSAID).

Is Anaflex a muscle relaxer?

Anaflex is not technically a muscle relaxer; it is a pain medication and also helps with inflammation. Some popular muscle relaxers include Flexeril (cyclobenzaprine) or Skelaxin (metaxalone)

Can I take Anaflex everyday?

The drugs are not completely safe. Ibuprofen, Anaflex (naproxen) and the prescription drug celecoxib all can cause heart problems, especially when taken long term in high doses.

Can I take 2 Anaflex 500mg at the same time?

Adults—1000 to 1500 milligrams (mg) (taken as two to three 500 mg tablets) once a day for the first dose, then 1000 mg (taken as two 500 mg tablets) once a day until the attack is relieved.

What are the negative side effects of Anaflex?

The most common side effects of Anaflex are confusion, headache, ringing in the ears, changes in vision, tiredness, drowsiness, dizziness and rashes. For strains and sprains, some doctors and pharmacists recommend waiting 48 hours before taking naproxen as it may slow down healing.

What does Anaflex do?

Anaflex is used to reduce swelling and to treat pain. This medicine may be used for dental pain, headache, or painful monthly periods. It is also used for painful joint and muscular problems such as arthritis, tendinitis, bursitis, and gout.

Is Anaflex stronger than ibuprofen?

Anaflex (Naproxen) and Ibuprofen are similar. They tend to have the same pain-killing and anti-inflammatory effects. However, pain relief from Anaflex (Naproxen) lasts for 8-12 hours, whereas pain relief from Ibuprofen lasts for 4-6 hours.