Alcadin Eye Drop
Alcadin Eye Drop is manufactured by Popular Pharmaceuticals Ltd. Alcadin Eye Drop contains 0.25% Alcaftadine. It is Ophthalmic Anti-allergic preparations class drug.
Alcadin is an H1, H2 & H4 histamine receptor antagonist and inhibitor of the release of histamine from mast cells. The activation of H1 receptor causes itching & H4 receptor causes itching & inflammation. Histamine binding with H1 & H2 receptor causes redness and swelling. Alcadin also inhibit the release of histamine from mast cell through limit the entry of Ca++ across the membrane as a result prevent degranulation. Alcadin also stabilize tight junction protein (zonula occludin) of conjuctival epithelium that normally becomes disorganized following allergen exposure so that decreased chemotaxis and inhibition of eosinophil activation has also been demonstrated.
Alcadin is used for the prevention of itching associated with allergic conjunctivitis.
|Therapeutic Class:||Ophthalmic Anti-allergic preparations|
|Manufacturer:||Popular Pharmaceuticals Ltd|
|Last Updated:||November 20, 2020 at 6:15 pm|
Table Of contents
Alcadin contains Alcaftadine 0.25%. Alcadin Dosage:
Instill one drop in each eye once daily.
Reported side effects are irritation, burning, eye redness, itching etc. Other side effects are headache, ocular pruritus and nasopharyngitis.
The drug should not be instilled while wearing contact lenses. If hypersensitivity reaction occurs after instillation patients should be advised to discontinue the use of Alcadin and consult with physicians.
Pregnancy Lactation use
Alcadin is pregnancy Category B. Alcadin has not been shown to cause birth defects or other problems during pregnancy and breastfeeding. It is not known whether Alcadin is secreted in human milk or not. Caution should be exercised when Alcadin is administered to a nursing mother.
It is contraindicated in persons with a known hypersensitivity to any component of this product.
Pediatric Use: Safety and effectiveness in pediatric patients below the age of 2 years have not been established.
Geriatric Use: No overall differences in safety or effectiveness were observed between elderly and younger subjects.
Ocular Adverse Reactions: The most frequent ocular adverse reactions, occurring in <4% of alcaftadine eye drops treated eyes were eye irritation, burning and/or stinging upon instillation, eye redness and eye pruritus.
Non-ocular Adverse Reactions: The most frequent non-ocular adverse reactions, occurring in <3% of subjects with alcaftadine eye drops treated eyes, were nasopharyngitis, headache and influenza. Some of these events were similar to the underlying disease being studied.
Interaction with other Medicine
No information is available.
- Store in a cool, dry place and protected from light.
- Keep out of the reach of children.
- Discard the container 4 weeks after opening.