Aerophin Solution for Inhalation

Aerophin Solution for Inhalation is manufactured by Incepta Pharmaceuticals Limited. Aerophin Solution for Inhalation contains 11.25 mg/0.5 ml Racepinephrine. It is Anaphylaxis class drug.

Aerophin works by stimulating α-adrenergic receptor in the airway with resulting tightening of the mucosa (mucosal vasoconstriction) and decreased fluid in the airway (subglottic edema) and by stimulation of α-adrenergic receptor causing relaxation of the bronchial smooth muscle.

Uses

For temporary relief of mild symptoms of intermittent asthma: 

  • Wheezing
  • Tightness of chest
  • Shortness of breath
Brand Name: Aerophin
Generic: Racepinephrine
Weight: 11.25 mg/0.5 ml
Type: Solution for Inhalation
Therapeutic Class: Anaphylaxis
Manufacturer: Incepta Pharmaceuticals Limited
Price: 0.00
Last Updated: November 22, 2020 at 6:15 pm

Dosage

Aerophin contains Racepinephrine 11.25 mg/0.5 ml. Aerophin Dosage:

Usual Adult Dose for Acute Asthma: For temporary relief of shortness of breath, tightness of chest, and wheezing due to bronchial asthma: Add 0.5 ml (contents of one vial) of solution to a hand-held rubber bulb nebulizer. 1 to 3 inhalations not more than every 3 hours.

Usual Pediatric Dose for Acute Asthma: For temporary relief of shortness of breath, tightness of chest, and wheezing due to bronchial asthma in children 4 years old and older: Add 0.5 ml (contents of one vial) of solution to a hand-held rubber bulb nebulizer: 1 to 3 inhalations not more than every 3 hours. The use of this product by children should be supervised by an adult.

 

Side Effects

Cardiovascular side effects have included elevations of heart rate and blood pressure. In smaller doses, racepinephrine has caused peripheral coronary arterial vasodilation, but in larger doses, racepinephrine has caused diffuse vasoconstriction. This has caused increased peripheral vascular resistance, which was important in patients with coronary artery disease (worsened myocardial ischemia/angina) or hypertension (risk of emergent hypertension/stroke).    

Arrhythmias, including fatal ventricular fibrillation, have been reported in patients with underlying cardiac disease. Rapid rises in blood pressure have produced cerebral hemorrhage, particularly in elderly patients with cardiovascular disease. Angina may occur in patients with coronary artery disease.    

Gastrointestinal side effects have included nausea and vomiting.    

Nervous system side effects have included fear, agitation, anxiety, tenseness, restlessness, headache, tremor, dizziness, lightheadedness, nervousness, sleeplessness, excitability, weakness, and increased parkinsonian tremors.    

Psychiatric side effects have included agitation, disorientation, impaired memory, aggressive or assautive behavior, hallucinations, and psychosis.

Precaution

 

Aerophin

Interaction

 

Pregnancy Lactation use

Aerophin has not been formally assigned to a pregnancy category by the FDA. There are no data on the excretion of racepinephrine into human milk.

Contraindication

Hypersansitivity

Special Warning

 

Acute Overdose

 

Interaction with other Medicine

 

Storage Condition

Protect from light. Avoid excessive heat. Protect from freezing. Store between 2°C and 25°C